Best practices in current models mimicking drug permeability in the gastrointestinal tract

Best practices in current models mimicking drug permeability in the gastrointestinal tract - An UNGAP review

Published:2022-03 Issue: Volume:170 Page:106098
ISSN:0928-0987
Container-title:European Journal of Pharmaceutical Sciences
language:en
Short-container-title:European Journal of Pharmaceutical Sciences

Author:

O'Shea Joseph P.,Augustijns Patrick,Brandl Martin,Brayden David J.,Brouwers Joachim,Griffin Brendan T.,Holm René,Jacobsen Ann-Christin,Lennernäs Hans,Vinarov Zahari,O'Driscoll Caitriona M.

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference376 articles.

1. Druggability and drug-likeness concepts in drug design: are biomodelling and predictive tools having their say?;Agoni;J. Mol. Model.,2020

2. In vitro and in vivo preclinical evaluation of a minisphere emulsion-based formulation (SmPill®) of salmon calcitonin;Aguirre;Eur. J. Pharm. Sci.,2015

3. IMI – oral biopharmaceutics tools project – evaluation of bottom-up PBPK prediction success part 4: prediction accuracy and software comparisons with improved data and modelling strategies;Ahmad;Eur. J. Pharm. Biopharm.,2020

4. Quantifying the effects of inactinvsIsoflurane anesthesia on gastrointestinal motility in rats using dynamic magnetic resonance imaging and spatio-temporal maps;Ailiani;Neurogastroenterol. Motil.,2014

5. In silico prediction of human oral absorption based on QSAR analyses of PAMPA permeability;Akamatsu;Chem. Biodivers.,2009

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