Application of a physiologically based pharmacokinetic model for the evaluation of single-point plasma phenotyping method of CYP2D6
Author:
Funder
Chinese National Natural Science Foundation
Beijing Key Laboratory
Publisher
Elsevier BV
Subject
Pharmaceutical Science
Reference24 articles.
1. The antitussive effect of dextromethorphan in relation to CYP2D6 activity;Abdul Manap;Br. J. Clin. Pharmacol.,1999
2. Assessment of activity levels for CYP2D6*1, CYP2D6*2, and CYP2D6*41 genes by population pharmacokinetics of dextromethorphan;Abduljalil;Clin. Pharmacol. Ther.,2010
3. Safety, tolerability, and pharmacokinetics of the N-methyl-d-aspartate antagonist dextrorphan in patients with acute stroke. Dextrorphan study group;Albers;Stroke,1995
4. The influence of CYP2D6 polymorphism and quinidine on the disposition and antitussive effect of dextromethorphan in humans;Capon;Clin. Pharmacol. Ther.,1996
5. In-vivo indices of CYP2D6 activity: comparison of dextromethorphan metabolic ratios in 4-h urine and 3-h plasma;Chládek;Eur. J. Clin. Pharmacol.,2000
Cited by 5 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Physiologically based pharmacokinetic (PBPK) modeling of the role of CYP2D6 polymorphism for metabolic phenotyping with dextromethorphan;Frontiers in Pharmacology;2022-10-24
2. The impact of CYP2D6*41 on CYP2D6 enzyme activity using phenotyping methods in urine, plasma, and saliva;Frontiers in Pharmacology;2022-08-30
3. Physiologically based pharmacokinetic (PBPK) modeling of the role of CYP2D6 polymorphism for metabolic phenotyping with dextromethorphan;2022-08-25
4. The Irrelevance of In Vitro Dissolution in Setting Product Specifications for Drugs Like Dextromethorphan That are Subject to Lysosomal Trapping;Journal of Pharmaceutical Sciences;2019-01
5. CYP2D6 Phenotyping Using Urine, Plasma, and Saliva Metabolic Ratios to Assess the Impact of CYP2D6∗10 on Interindividual Variation in a Chinese Population;Frontiers in Pharmacology;2017-05-02
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