Phenothiazines solution complexity – Determination of pKa and solubility-pH profiles exhibiting sub-micellar aggregation at 25 and 37°C

Author:

Pobudkowska Aneta,Ràfols Clara,Subirats Xavier,Bosch Elisabeth,Avdeef Alex

Funder

Warsaw University of Technology

Spanish government

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference60 articles.

1. Micellar properties of drugs: properties of micellar aggregates of phenothiazines and their aqueous solutions;Attwood;J. Pharm. Sci.,1974

2. Calorimetric study of the influence of electrolyte on the micellization of phenothiazine drugs in aqueous solution;Attwood;J. Phys. Chem. B,1997

3. pH-metric log P. 2. Refinement of partition coefficients and ionization constants of multiprotic substances;Avdeef;J. Pharm. Sci.,1992

4. Sirius Technical Application Notes (STAN);Avdeef,1994

5. pH-metric solubility. 1. Solubility-pH profiles from Bjerrum plots. Gibbs buffer and pKa in the solid state;Avdeef;Pharm. Pharmacol. Commun.,1998

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