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Palmitic acid induces nDNA release to cytosol and promotes microglial M1 polarization via cGAS-STING signaling pathway

  • Published:2023-01 Issue:1 Volume:1870 Page:119385
  • ISSN:0167-4889
  • Container-title:Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  • language:en
  • Short-container-title:Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Author:

Deng Yuping,Yi Xiaoqing,Gong Yuxiang,Zhou Liyan,Xie Dongxue,Wang Jufen,Liu Zhilin,Zhang Yinhao,Wu Wenhe

Funder

Health Commission of Zhejiang Province

National Natural Science Foundation of China

Wenzhou Municipal Science and Technology Bureau

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology

Reference60 articles.

1. Obesity, immunity, and cancer;Rathmell;N. Engl. J. Med.,2021

2. Dietary fat, but not protein or carbohydrate, regulates energy intake and causes adiposity in mice;Hu;Cell Metab.,2018

3. The Major Cap-binding Protein eIF4E Regulates Lipid Homeostasis and Diet-Induced Obesity;Conn,2021

4. Monounsaturated fatty acids in obesity-related inflammation;Ravaut;Int. J. Mol. Sci.,2020

5. Palmitic acid is an intracellular signaling molecule involved in disease development;Fatima;Cell. Mol. Life Sci.,2019
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