Dual-agonist occupancy of orexin receptor 1 and cholecystokinin A receptor heterodimers decreases G-protein–dependent signaling and migration in the human colon cancer cell line HT-29-Reference-Cited by-同舟云学术

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Dual-agonist occupancy of orexin receptor 1 and cholecystokinin A receptor heterodimers decreases G-protein–dependent signaling and migration in the human colon cancer cell line HT-29

Published:2017-07 Issue:7 Volume:1864 Page:1153-1164
ISSN:0167-4889
Container-title:Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
language:en
Short-container-title:Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Author:

Bai Bo,Chen Xiaoyu,Zhang Rumin,Wang Xin,Jiang Yunlu,Li Dandan,Wang Zhengwen,Chen Jing

Funder

National Nature Science Foundation of China

National Nature Science Foundation of Shandong Province

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology

Reference38 articles.

1. Orexin receptors exert a neuroprotective effect in Alzheimer's disease (AD) via heterodimerization with GPR103;Davies;Sci. Rep.,2015

2. Heterodimerization of human apelin and bradykinin 1 receptors: novel signal transduction characteristics;Bai;Cell. Signal.,2014

3. Receptors for dopamine and somatostatin: formation of hetero-oligomers with enhanced functional activity;Rocheville;Science,2000

4. Heterodimerization of human orexin receptor 1 and kappa opioid receptor promotes protein kinase A/cAMP-response element binding protein signaling via a Galphas-mediated mechanism;Chen;Cell. Signal.,2015

5. The orexin receptor OX(1)R in colon cancer: a promising therapeutic target and a new paradigm in G protein-coupled receptor signalling through ITIMs;Laburthe;Br. J. Pharmacol.,2012

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