Structure-based functional analysis of BRCA1 RING domain variants: Concordance of computational mutagenesis, experimental assay, and clinical data
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Biochemistry,Biophysics
Reference40 articles.
1. A brief history of human disease genetics;Claussnitzer;Nature,2020
2. The genetics of breast cancer risk in the post-genome era: thoughts on study design to move past BRCA and towards clinical relevance;Skol;Breast Cancer Res.,2016
3. Molecular trajectory of BRCA1 and BRCA2 mutations;Hatano;Front. Oncol.,2020
4. Accurate classification of BRCA1 variants with saturation genome editing;Findlay;Nature,2018
5. A multiplex homology-directed DNA repair assay reveals the impact of more than 1,000 BRCA1 missense substitution variants on protein function;Starita;Am. J. Hum. Genet.,2018
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