A simple linearization method unveils hidden enzymatic assay interferences-Reference-Cited by-同舟云学术

A simple linearization method unveils hidden enzymatic assay interferences

Published:2019-09 Issue: Volume:252 Page:106193
ISSN:0301-4622
Container-title:Biophysical Chemistry
language:en
Short-container-title:Biophysical Chemistry

Author:

Pinto Maria Filipa,Ripoll-Rozada Jorge,Ramos Helena,Watson Emma E.,Franck Charlotte,Payne Richard J.,Saraiva Lucília,Pereira Pedro José Barbosa,Pastore Annalisa,Rocha Fernando,Martins Pedro M.

Funder

FEDER—Fundo Europeu de Desenvolvimento Regional funds

COMPETE 2020—Operational Programme for Competitiveness and Internationalisation

FCT—Fundação para a Ciência e a Tecnologia/Ministério da Ciência, Tecnologia e Ensino Superior

PIDDAC

Norte Portugal Regional Operational Programme

PORTUGAL 2020 Partnership Agreement

FCT – Fundação para a Ciência e a Tecnologia

Doctoral Program in Biomedical Sciences

BiotechHealth Programme

Publisher

Elsevier BV

Subject

Organic Chemistry,Biochemistry,Biophysics

Reference54 articles.

1. Mechanistic enzymology in drug discovery: a fresh perspective;Holdgate;Nat. Rev. Drug Discov.,2018

2. The druggable genome: evaluation of drug targets in clinical trials suggests major shifts in molecular class and indication;Rask-Andersen;Annu. Rev. Pharmacol. Toxicol.,2014

3. Apparent activity in high-throughput screening: origins of compound-dependent assay interference;Thorne;Curr. Opin. Chem. Biol.,2010

4. The ecstasy and agony of assay interference compounds;Aldrich;ACS Cent. Sci.,2017

5. One pot synthesis of GDP-mannose by a multi-enzyme cascade for enzymatic assembly of lipid-linked oligosaccharides;Rexer;Biotechnol. Bioeng.,2018

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