Loss of Huntingtin stimulates capture of retrograde dense-core vesicles to increase synaptic neuropeptide stores
Author:
Funder
NIH
Publisher
Elsevier BV
Subject
Cell Biology,General Medicine,Histology,Pathology and Forensic Medicine
Reference24 articles.
1. Vesicle capture, not delivery, scales up neuropeptide storage in neuroendocrine terminals;Bulgari;Proc. Natl. Acad. Sci. U. S. A.,2014
2. Huntingtin coordinates the dynein-mediated dynamic positioning of endosomes and lysosomes;Caviston;Mol. Biol. Cell,2011
3. Mycalolide B dissociates dynactin and abolishes retrograde axonal transport of dense-core vesicles;Cavolo;Mol. Biol. Cell,2015
4. Activity induces Fmr1-sensitive synaptic capture of anterograde circulating neuropeptide vesicles;Cavolo;J. Neurosci.,2016
5. Huntingtin-associated protein 1 (HAP1) interacts with the p150Glued subunit of dynactin;Engelender;Hum. Mol. Genet.,1997
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1. Huntingtin lowering impairs the maturation and synchronized synaptic activity of human cortical neuronal networks derived from induced pluripotent stem cells;Neurobiology of Disease;2024-10
2. Huntingtin is essential for synaptic plasticity in the adult hippocampus;2022-10-05
3. Huntingtin and the Synapse;Frontiers in Cellular Neuroscience;2021-06-15
4. Excess Rab4 rescues synaptic and behavioral dysfunction caused by defective HTT-Rab4 axonal transport in Huntington’s disease;Acta Neuropathologica Communications;2020-07-01
5. Sentryn and SAD Kinase Link the Guided Transport and Capture of Dense Core Vesicles in Caenorhabditis elegans;Genetics;2018-10-31
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