Par-4 mediated Smad4 induction in PDAC cells restores canonical TGF-β/ Smad4 axis driving the cells towards lethal EMT-Reference-Cited by-同舟云学术

Par-4 mediated Smad4 induction in PDAC cells restores canonical TGF-β/ Smad4 axis driving the cells towards lethal EMT

Published:2020-05 Issue:4 Volume:99 Page:151076
ISSN:0171-9335
Container-title:European Journal of Cell Biology
language:en
Short-container-title:European Journal of Cell Biology

Author:

Mohd Faheem Mir,Rasool Reyaz ur,Ahmad Syed Mudabir,Jamwal Vijay Lakshmi,Chakraborty Souneek,Katoch Archana,Gandhi Sumit G.,Bhagat Madhulika,Goswami Anindya

Funder

Council of Scientific and Industrial Research, India

University of Tennessee

University of Kentucky

Publisher

Elsevier BV

Subject

Cell Biology,General Medicine,Histology,Pathology and Forensic Medicine

Reference67 articles.

1. Overexpression of the c-Myc oncoprotein blocks the growth-inhibitory response but is required for the mitogenic effects of transforming growth factor beta 1;Alexandrow;Proc. Natl. Acad. Sci.,1995

2. Par‐4 dependent modulation of cellular β‐catenin by medicinal plant natural product derivative 3‐azido Withaferin A;Amin;Mol. Carcinog.,2016

3. Cloning and expression analysis of chalcone synthase gene from Coleus forskohlii;Awasthi;J. Genet.,2016

4. PAR-4 as a possible new target for pancreatic cancer therapy;Azmi;Expert Opin. Ther. Targets,2010

5. Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer;Bardeesy;Genes Dev.,2006

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