Hypoxia-activated prodrugs and (lack of) clinical progress: The need for hypoxia-based biomarker patient selection in phase III clinical trials
Author:
Publisher
Elsevier BV
Subject
Radiology Nuclear Medicine and imaging,Oncology
Reference122 articles.
1. Hypoxia–a key regulatory factor in tumour growth;Harris;Nat Rev Cancer,2002
2. Biological consequences of radiation-induced DNA damage: relevance to radiotherapy;Lomax;Clin Oncol (R Coll Radiol),2013
3. The hypoxic cell: a target for selective cancer therapy–eighteenth Bruce F. Cain Memorial Award lecture;Brown;Cancer Res,1999
4. Exploiting tumour hypoxia in cancer treatment;Brown;Nat Rev Cancer,2004
5. Tumour hypoxia affects the responsiveness of cancer cells to chemotherapy and promotes cancer progression;Cosse;Anti-Cancer Agents Med Chem,2008
Cited by 90 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. The cellular-centered view of hypoxia tumor microenvironment: Molecular mechanisms and therapeutic interventions;Biochimica et Biophysica Acta (BBA) - Reviews on Cancer;2024-09
2. Tailoring polymeric nanocarriers for hypoxia-specific drug release: Insights into design and applications in clinics;Chemical Engineering Journal;2024-09
3. Recent Advances in the Application of Nitro(het)aromatic Compounds for Treating and/or Fluorescent Imaging of Tumor Hypoxia;Molecules;2024-07-25
4. Hypoxia‐Responsive Prodrug of ATR Inhibitor, AZD6738, Selectively Eradicates Treatment‐Resistant Cancer Cells;Advanced Science;2024-07-08
5. The tumor microenvironment’s in pancreatic cancer: Effects on immunotherapy success and novel strategies to overcome the hostile environment;Pathology - Research and Practice;2024-07
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3