Inhibitors of sterol synthesis. Submicromolar 14 alpha-ethyl-5 alpha-cholest-7-ene-3 beta, 15 alpha-diol causes a major modification of the sterol composition of CHO-K1 cells and a marked change in cell morphology.-Reference-Cited by-同舟云学术

Inhibitors of sterol synthesis. Submicromolar 14 alpha-ethyl-5 alpha-cholest-7-ene-3 beta, 15 alpha-diol causes a major modification of the sterol composition of CHO-K1 cells and a marked change in cell morphology.

Published:1994-07 Issue:7 Volume:35 Page:1251-1266
ISSN:0022-2275
Container-title:Journal of Lipid Research
language:en
Short-container-title:Journal of Lipid Research

Author:

Izumi A,Pinkerton F.D,Nelson S.O,Pyrek J.S,Neill P.J,Smith J H,Schroepfer G.J

Publisher

Elsevier BV

Subject

Cell Biology,Endocrinology,Biochemistry

Reference69 articles.

1. 14α-Ethyl-5α-cholest-7-ene-3β,15α-diol, an extraordinarily potent inhibitor of sterol biosynthesis in animal cells;Schroepfer;J. Am. Chem. Soc.,1977

2. Inhibitors of sterol biosynthesis. Synthesis of 14α-alkyl substituted 15-oxygenated sterols;Parish;Chem. Phys. Lipids.,1979

3. Structure and synthesis of 14α-ethyl-5α-cholest-7-ene-3β,15α-diol di-p-bromobenzoate;Monger;Acta Crystal-logr.,1980

4. Inhibition of sterol biosynthesis in animal cells by 14α-alkyl-substituted 15-oxygenated sterols;Schroepfer;J. Lipid Res.,1979

5. Inhibition of cholesterol biosynthesis in cell-free preparations of rat liver by 14α-ethyl-5α-cholest-7-ene-3β,15α:-diol;Raulston;Biochem. Int.,1980

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2. Sterol synthesis. A timely look at the capabilities of conventional and silver ion high performance liquid chromatography for the separation of C27 sterols related to cholesterol biosynthesis;Journal of Lipid Research;1997-12

3. Inhibitors of sterol synthesis. Synthesis and spectral properties of 3β-hydroxy-25,26,26,26,27,27,27-heptafluoro-5α-cholestan-15-one;Chemistry and Physics of Lipids;1997-04

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