3D-QSAR CoMFA analysis of C5 substituted pyrrolotriazines as HER2 (ErbB2) inhibitors

Author:

Awale Mahendra,Mohan C. Gopi

Publisher

Elsevier BV

Subject

Materials Chemistry,Computer Graphics and Computer-Aided Design,Physical and Theoretical Chemistry,Spectroscopy

Reference15 articles.

1. Role of HER2/neu in tumor progression and therapy;Menard;Cell Mol. Life Sci.,2004

2. Pharmacogenomics of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors;Jimeno;Biochim. Biophys. Acta (BBA)-Rev. Cancer,2006

3. ErbB-2 amplification inhibits down-regulation and induces constitutive activation of both ErbB-2 and epidermal growth factor receptors;Worthylake;J. Biol. Chem.,1999

4. Genetic alterations in intraductal and invasive breast cancer;Van de Vijver;Eur. J. Cancer,2001

5. Untangling the ErbB signalling network;Yarden;Nat. Rev. Mol. Cell Biol.,2001

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