A theoretical study on mechanism of the anticancer drug camptothecin's E-ring-opening

Author:

Zou Hui-Yuan,Zhao Dong-Xia,Yang Zhong-Zhi

Publisher

Elsevier BV

Subject

Materials Chemistry,Computer Graphics and Computer-Aided Design,Physical and Theoretical Chemistry,Spectroscopy

Reference51 articles.

1. Plant antitumor agents. I. The isolation and structure of camptothecin, a novel alkaloidal leukemia and tumor inhibitor from Camptotheca acuminata;Wall;Journal of the American Chemical Society,1966

2. Camptothecin and taxol discovery to clinic—thirteenth Bruce F. Cain memorial award lecture;Wall;Cancer Research,1995

3. Solvent effects on the valence UV–vis absorption spectra of Topotecan anticancer drug in aqueous solution at room temperature: a nanoseconds time-scale TD-DFT/MD computational study;Zazza;Journal of Physical Chemistry B,2010

4. Camptothecin and taxol discovery to clinic;Wall;Medicinal Research Reviews,1998

5. Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I;Hsiang;Journal of Biological Chemistry,1985

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