Significantly Decreased Mortality in a Large Cohort of Coronavirus Disease 2019 (COVID-19) Patients Transfused Early with Convalescent Plasma Containing High-Titer Anti–Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike Protein IgG

Author:

Salazar EricORCID,Christensen Paul A.,Graviss Edward A.ORCID,Nguyen Duc T.ORCID,Castillo BrianORCID,Chen Jian,Lopez Bevin V.,Eagar Todd N.,Yi Xin,Zhao Picheng,Rogers John,Shehabeldin Ahmed,Joseph DavidORCID,Masud Faisal,Leveque Christopher,Olsen Randall J.,Bernard David W.ORCID,Gollihar Jimmy,Musser James M.

Funder

Fondren Foundation

Houston Methodist Hospital

Houston Methodist Research Institute

Publisher

Elsevier BV

Subject

Pathology and Forensic Medicine

Reference22 articles.

1. COVID-19 Dashboard by the Center for Systems Science and Engineering (CSSE) at Johns Hopkins University (JHU),2020

2. Effect of convalescent plasma on mortality among hospitalized patients with COVID-19: initial three-month experience;Joyner;medRxiv,2020

3. Treatment of coronavirus disease 2019 patients with convalescent plasma reveals a signal of significantly decreased mortality;Salazar;Am J Pathol,2020

4. Evidence favouring the efficacy of convalescent plasma for COVID-19 therapy;Klassen;medRxiv,2020

5. Relationship between anti-spike protein antibody titers and SARS-CoV-2 in vitro virus neutralization in convalescent plasma;Salazar;bioRxiv,2020

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