Paradoxical urinary phenytoin metabolite (S)/(R) ratios in CYP2C19*1/*2 patients

Author:

Argikar Upendra A.,Cloyd James C.,Birnbaum Angela K.,Leppik Ilo E.,Conway Jeannine,Kshirsagar Smita,Oetting William S.,Klein Erin C.,Remmel Rory P.

Publisher

Elsevier BV

Subject

Neurology (clinical),Neurology

Reference35 articles.

1. CYP2C9, CYP2C19, ABCB1 (MDR1) genetic polymorphisms and phenytoin metabolism in a Black Beninese population;Allabi;Pharmacogenet. Genom.,2005

2. Frequency of cytochrome P450 CYP2C9 variants in a Turkish population and functional relevance for phenytoin;Aynacioglu;Br. J. Clin. Pharmacol.,1999

3. Roles of cytochrome P4502C9 and cytochrome P4502C19 in the stereoselective metabolism of phenytoin to its major metabolite;Bajpai;Drug Metab. Dispos.,1996

4. Allelic and functional variability of cytochrome P4502C9;Bhasker;Pharmacogenetics,1997

5. Phenytoin and other hydantoins: chemistry and biotransformation;Browne,2002

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