AQB-565 shows promise in preclinical testing in the model of epileptic spasms during infancy: Head-to-head comparison with ACTH-Reference-Cited by-同舟云学术

AQB-565 shows promise in preclinical testing in the model of epileptic spasms during infancy: Head-to-head comparison with ACTH

Published:2019-05 Issue: Volume:152 Page:31-34
ISSN:0920-1211
Container-title:Epilepsy Research
language:en
Short-container-title:Epilepsy Research

Author:

Chern Chian-Ru,Chern Chian-Jiang,Velíšková Jana,Velíšek Libor

Funder

Aequus Biopharma, Inc.

NIH

Publisher

Elsevier BV

Subject

Clinical Neurology,Neurology

Reference22 articles.

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2. CPP-115, a vigabatrin analogue, decreases spasms in the multiple-hit rat model of infantile spasms;Briggs;Epilepsia,2014

3. Corticotropin (ACTH) acts directly on amygdala neurons to down-regulate corticotropin-releasing hormone gene expression;Brunson;Ann. Neurol.,2001

4. Validation of the rat model of cryptogenic infantile spasms;Chachua;Epilepsia,2011

5. Estradiol does not affect spasms in the betamethasone-NMDA rat model of infantile spasms;Chachua;Epilepsia,2016

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