High vigabatrin dosage is associated with lower risk of infantile spasms relapse among children with tuberous sclerosis complex

Author:

Hussain Shaun A.,Schmid Ernst,Peters Jurriaan M.,Goyal Monisha,Bebin E. Martina,Northrup Hope,Sahin Mustafa,Krueger Darcy A.,Wu Joyce Y.,Pearson Deborah,Williams Marian E.,Hanson Ellen,Bing Nicole,Kent Bridget,O’Kelley Sarah,Filip-Dhima Rajna,Dies Kira,Bruns Stephanie,Scherrer Benoit,Cutter Gary,Murray Donna S.,Roberds Steven L.

Funder

Epilepsy Therapy Project

Milken Family Foundation

Elsie and Isaac Fogelman Endowment, Eisai

Lundbeck

INSYS

GW Pharmaceuticals

UCB

NIH

Roche

Novartis

Pfizer

LAM Therapeutics

Novartis Pharmaceuticals

Novartis Pharmaceuticals Inc.

Today and Tomorrow Children’s Fund, Department of Defense/ Congressionally Directed Medical Research Program

National Institute of Neurological Diseases and Stroke

Elsie and Isaac Fogelman Endowment

Hughes Family Foundation

UCLA Children’s Discovery and Innovation Institute

Department of Defense

Congressionally Directed Medical Research Program

Today’s and Tomorrow’s Children Fund from UCLA Mattel Children’s Hospital

Developmental Synaptopathies Consortium

NCATS

National Institute of Mental Health

National Institute of Child Health and Human Development

National Center for Advancing Translational Sciences

Publisher

Elsevier BV

Subject

Clinical Neurology,Neurology

Reference29 articles.

1. Randomised, placebo-controlled study of vigabatrin as first-line treatment of infantile spasms;Appleton;Epilepsia,1999

2. High-dose corticotropin (ACTH) versus prednisone for infantile spasms: a prospective, randomized, blinded study;Baram;Pediatrics,1996

3. Randomized trial comparing vigabatrin and hydrocortisone in infantile spasms due to tuberous sclerosis;Chiron;Epilepsy Res.,1997

4. Vigabatrin-associated reversible MRI signal changes in patients with infantile spasms;Dracopoulos;Epilepsia,2010

5. Severe persistent visual field constriction associated with vigabatrin;Eke;BMJ,1997

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