In vivo genotoxic evaluation of the furylethylene derivative 1-(5-bromofur-2-yl)-2-nitroethene in mouse bone marrow

Author:

Borroto Jorge I. González,Creus Amadeu,Marcos Ricard,Zapatero Jorge

Publisher

Elsevier BV

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,General Medicine

Reference24 articles.

1. In vitro evaluation of G1: a novel antimicrobial compound;Blondeau;Int. J. Antimicrob. Agents,1999

2. Castañedo, N., Goizueta, R., Pérez, J., González, J., Silveira, E., Cuesta, M., Martínez, A., Lugo, E., Estrada, E., Carta, A.C., Navia, O., Delgado, M.S., 1994. Procedure for the Obtainment of 1-(5-Bromofur-2-yl)-2-Bromo-2-Nitroethene and its Microcide Action, Cuban Patent 22446. European Patent, Application Number 95500056.7. Canadian Patent, Application Number 2,147,594. Japanese Patent, Application Number 222002. U.S. Patent, Application Number 60008011.

3. Biotransformation reactions of five-membered aromatic heterocyclic rings;Dalvie;Chem. Res. Toxicol.,2002

4. Mechanistic interpretation of the genotoxicity of nitrofurans (antibacterial agents) using quantitative structure-activity relationships and comparative molecular field analysis;Debnath;J. Med. Chem.,1993

5. Structure-mutagenicity relationships in 2-furylethylene derivatives. A molecular orbital study of the role of nitro groups;Estrada;Mutat. Res.,1998

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