Acute cadmium exposure induces GSDME-mediated pyroptosis in triple-negative breast cancer cells through ROS generation and NLRP3 inflammasome pathway activation

Author:

Tang Jie,Bei Mingrong,Zhu Jia,Xu Guangtao,Chen Deqing,Jin Xin,Huang Jianzhong,Dong Jingjian,Shi Lili,Xu LongORCID,Hu Bo

Publisher

Elsevier BV

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,General Medicine

Reference40 articles.

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2. Overview of cadmium thyroid disrupting effects and mechanisms;Buha;Int. J. Mol. Sci.,2018

3. Involvement of E2F1 transcriptional activity in cadmium-induced cell-cycle arrest at G1 in human lung fibroblasts;Choi;Environ. Mol. Mutagen.,2011

4. Sirtuin-1 ameliorates cadmium-induced endoplasmic reticulum stress and pyroptosis through XBP-1s deacetylation in human renal tubular epithelial cells;Chou;Arch. Toxicol.,2019

5. GSDME and its role in cancer: from behind the scenes to the front of the stage;De Schutter;Int. J. Cancer,2020

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