An improved in vitro method for screening toxin and medicine targeting CYP2E1

Author:

Wang Meng,Zhou Zhaoxiang,Wang Jian,Zhang Xiaoying

Funder

High-end Foreign Experts Recruitment Program of State Administration of Foreign Experts Affairs

Key Construction Program of International Cooperation Base in S&T, Shaanxi Province

Publisher

Elsevier BV

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,General Medicine

Reference31 articles.

1. Isolation of mitochondria from liver and extraction of total RNA and protein: analyses of microRNA and protein expressions;Borralho;Methods Mol. Biol.,2015

2. Tissue-specific expression and methylation of the human Cyp2e1 gene;Botto;Biochem. Pharmacol.,1994

3. Hormone- and substrate-regulated intracellular degradation of cytochrome P450 (2E1) involving MgATP-activated rapid proteolysis in the endoplasmic reticulum membranes;Eliasson;J. Biol. Chem.,1992

4. Role of cytochromes P450 in chemical toxicity and oxidative stress: studies with CYP2E1;Gonzalez;Mutat. Res.,2005

5. Coordinate regulation of Cyp2e1 by beta-catenin- and hepatocyte nuclear factor 1alpha-dependent signaling;Groll;Toxicology,2016

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