Diallyl disulfide improves lipid metabolism by inhibiting PCSK9 expression and increasing LDL uptake via PI3K/Akt-SREBP2 pathway in HepG2 cells-Reference-Cited by-同舟云学术

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Diallyl disulfide improves lipid metabolism by inhibiting PCSK9 expression and increasing LDL uptake via PI3K/Akt-SREBP2 pathway in HepG2 cells

Published:2021-01 Issue:1 Volume:31 Page:322-332
ISSN:0939-4753
Container-title:Nutrition, Metabolism and Cardiovascular Diseases
language:en
Short-container-title:Nutrition, Metabolism and Cardiovascular Diseases

Author:

Wu Ya-Ru,Li Liang,Sun Xian-Chang,Wang Jun,Ma Chun-Yan,Zhang Yue,Qu Hui-Lin,Xu Rui-Xia,Li Jian-Jun

Funder

Peking Union Medical College

Chinese Academy of Medical Sciences

Publisher

Elsevier BV

Subject

Cardiology and Cardiovascular Medicine,Nutrition and Dietetics,Endocrinology, Diabetes and Metabolism,Medicine (miscellaneous)

Reference40 articles.

1. Diabetes promotes an inflammatory macrophage phenotype and atherosclerosis through acyl-CoA synthetase 1;Kanter;Proc Natl Acad Sci U S A,2012

2. Inflammation may be a bridge connecting hypertension and atherosclerosis;Li;Med Hypotheses,2005

3. Executive summary: heart disease and stroke statistics--2016 update: a report from the American Heart Association;Mozaffarian;Circulation,2016

4. PCSK9: a key modulator of cardiovascular health;Seidah;Circ Res,2014

5. Role of PCSK9 in lipid metabolism and atherosclerosis;Lin;Biomed Pharmacother,2018

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4. Effects of diallyl disulfide administration on insulin resistance in high-fat diet-fed mice;Nutrition;2024-02

5. High-salt diet induces dyslipidemia through the SREBP2/PCSK9 pathway in dahl salt-sensitive rats;Biochimie;2024-01

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