Hepatic and intestinal metabolism of indinavir, an HIV protease inhibitor, in rat and human microsomes

Author:

Chiba Masato,Hensleigh Michelle,Lin Jiunn H.

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference22 articles.

1. Small intestinal cytochrome P450;Kaminsky;Crit Rev Toxicol,1992

2. Characterization of rat small intestinal cytochrome P-450 composition and inducibility;Zhang;Drug Metab Dispos,1996

3. Cytochrome P450 isoenzymes, epoxide hydrolase and glutathione transferases in rat and human hepatic and extra hepatic tissues;de Waziers;J Pharmacol Exp Ther,1990

4. Heterogeneity of cytochrome P450IIIA expression in rat gut epithelia;Kolars;Gastroenterology,1992

5. Bioavailability of cyclosporine with concomitant rifampin administration is markedly less than predicted by hepatic en zyme induction;Hebert;Clin Pharmacol Ther,1992

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