Hypertrophy of brown adipocytes in brown and white adipose tissues and reversal of diet-induced obesity in rats treated with a β3-adrenoceptor agonist

Author:

Ghorbani Masoud,Claus Thomas H.,Himms-Hagen Jean

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference34 articles.

1. Disodium (R,R)-5-[2- [[2 - (3-chlorophenyl) - 2 - hydroxyethyl]- amino]propyl]-1,3-benzodioxole-2,2-dicarboxylate (CL 316,243). A potent β-adrenergic agonist virtually specific for β3 receptors. A promising antidiabetic and antiobesity agent;Bloom;J Med Chem,1992

2. Beta-3 adrenoceptor selectivity of the Dioxolane dicarboxylate phenethanolamines;Dolan;J Pharmacol Exp Ther,1994

3. Antidiabetic and antiobesity effects of a highly selective β3-adrenoceptor agonist (CL 316,243);Largis;Drug Dev Res,1994

4. The potential role of beta-3 adrenoceptor agonists in the treatment of obesity and diabetes;Himms-Hagen;Curr Opin Endocrinel Diabetes,1996

5. Effect of CL-316,243, a thermogenic β3-agonist, on energy balance and brown and white adipose tissues in rats;Himms-Hagen;Am J Physiol,1994

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