Effect of metformin on fatty acid and glucose metabolism in freshly isolated hepatocytes and on specific gene expression in cultured hepatocytes11Abbreviations: CPT I or II, carnitine palmitoyltransferase I or II; mtHMG-CoA synthase, mitochondrial hydroxymethylglutaryl-CoA synthase; Glc-6-Pase, glucose-6-phosphatase; PEPCK, phosphoenolpyruvate carboxykinase; GK, glucokinase; L-PK, liver-type pyruvate kinase; and ACS, acyl-CoA synthetase.

Author:

Fulgencio Jean-Pierre,Kohl Claude,Girard Jean,Pégorier Jean-Paul

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference42 articles.

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2. Effects of metformin in obese patients with impaired glucose tolerance;Scheen;Diabetes Metab Rev,1995

3. Metformin. A review of its pharmacological properties and therapeutic use in non-insulin-dependent diabetes Mellitus;Dunn;Drugs,1995

4. Membrane physiology as basis for the cellular effects of metformin in insulin resistance and diabetes;Wiernsperger;Diabetes & Metab,1999

5. Biguanides may produce hypoglycemic action in isolated rat hepatocytes through their effects on l-alanine transport;Komori;Diabetes Res Clin Pract,1993

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