Exendin-4 increases insulin sensitivity via a PI-3-kinase-dependent mechanism: contrasting effects of GLP-1

Author:

Idris Iskandar,Patiag Divina,Gray Samuel,Donnelly Richard

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference20 articles.

1. Additive insulinotropic effects of exogenous synthetic human gastric inhibitory polypeptide and glucagons-like peptide-1-(7-36) amide infused at near-physiological insulinotropic hormone and glucose concentrations;Nauck;J. Clin. Endocrinol. Metab.,1993

2. Reduced postprandial concentrations of intact biologically active glucagons like peptide-1 in Type 2 diabetic patients;Vilsboll;Diabetes,2001

3. Gastric emptying, glucose responses, and insulin secretion after a liquid test meal: effects of exogenous glucagons like peptide-1-(7-36) amide in type II (noninsulin-dependent) diabetic patients;Willms;J. Clin. Endocrinol. Metab.,1996

4. Glucagonostatic and insulinotropic action of glucagon-like peptide-1 (7-36) amide;Komatsu;Diabetes,1989

5. Antidiabetogenic effect of glucagons like peptide-1 (7-36) amide in normal subjects and patients with diabetes mellitus;Gutniak;New Engl. J. Med.,1992

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