Involvement of oxygen radicals in cytarabine-induced apoptosis in human polymorphonuclear cells11Abbreviations: ROS, reactive oxygen species; PMNs, polymorphonuclear neutrophils; SOD, superoxide dismutase; Ara-C, cytarabine; Ara-CTP, cytarabine 5′-triphosphate; O2−, superoxide anion; H2O2, hydrogen peroxide; f-MLP, N-Formyl-Met-Leu-Phe; PMA, phorbol 12-myristate 13-acetate; cyt c, cytochrome c; H7, 1-(5-isoquinolinylsulfonyl)-2-methylpiperazine; MTT, (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide; thiazolyl blue); MoAb, monoclonal antibody; NAC, N-acetyl-l-cysteine; DCFH-DA, 2′,7′-dichlorofluorescin diacetate; DCF, 2′,7′-dichlorofluorescein; DCFH, dichlorofluorescin; and DPI, diphenyleneiodonium chloride.
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Published:2001-04
Issue:8
Volume:61
Page:1033-1040
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ISSN:0006-2952
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Container-title:Biochemical Pharmacology
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language:en
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Short-container-title:Biochemical Pharmacology
Author:
Iacobini Metello,Menichelli Adriana,Palumbo Giuseppe,Multari Giuseppe,Werner Beate,Del Principe Domenico
Subject
Pharmacology,Biochemistry
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