Bleomycin genotoxicity and amifostine (WR-2721) cell protection in normal leukocytes vs. K562 tumoral cells

Author:

Buschini Annamaria,Alessandrini Chiara,Martino Anna,Pasini Luca,Rizzoli Vittorio,Carlo-Stella Carmelo,Poli Paola,Rossi Carlo

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference27 articles.

1. Chemoprotection in anticancer therapy: the emerging role of amifostine (WR-2721);Kurbacher;Anticancer Res.,1998

2. Amifostine: a selective cytoprotective agent of normal tissues from chemo-radiotherapy induced toxicity (review);Orditura;Oncol. Rep.,1999

3. In vitro antioxidant properties of amifostine (WR-2721, ethyol);Marzatico;Cancer Chemother. Pharmacol.,2000

4. In vitro effect of amifostine on haematopoietic progenitors exposed to carboplatin and non-alkylating antineoplatic drugs: haematoprotection acts as a drug-specific progenitor rescue;Pierelli;Br. J. Cancer,1998

5. Genotoxicity of bleomycin;Povirk;Mutat. Res.,1991

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