Salvicine, a novel DNA topoisomerase II inhibitor, exerting its effects by trapping enzyme-DNA cleavage complexes 1 1Abbreviations: ADM, adriamycin; VP16, etoposide; Topo, topoisomerase; kDNA, knetoplast DNA; HCPT, hydrocamptothecin; SC, supercoiled form; RLX, relaxed form; LNR, linear form; and NC, nicked form.

Author:

Meng Ling-hua,Zhang Jin-shen,Ding Jian

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

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