α-Fluoro-β-alanine: Effects on the antitumor activity and toxicity of 5-fluorouracil

Author:

Cao Shousong,Baccanari David P,Rustum Youcef M,Davis Stephen T,Tansik Robert L,Porter David J.T,Spector Thomas

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference22 articles.

1. Mechanism-based inactivation of dihydropyrimidine dehydrogenase by 5-ethynyluracil;Porter;J Biol Chem,1992

2. 5-Ethynyluracil (776C85);Spector;Biochem Pharmacol,1993

3. 5-Ethynyluracil (776C85);Baccanari;Proc Natl Acad Sci USA,1993

4. 5-Fluorouracil catabolism in rats is decreased by 5-ethynyluracil (776C85), an inactivator of uracil reductase;Lambe;Proc Am Assoc Cancer Res,1995

5. Studies on fluorinated pyrimidines. XVI. Metabolism of 5-fluorouracil-2-C14 and 5-fluoro-2′-deoxyuridine-C14 in cancer patients;Mukherjee;Cancer Res,1963

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