Addition of iptacopan, an oral factor B inhibitor, to eculizumab in patients with paroxysmal nocturnal haemoglobinuria and active haemolysis: an open-label, single-arm, phase 2, proof-of-concept trial-Reference-Cited by-同舟云学术

Addition of iptacopan, an oral factor B inhibitor, to eculizumab in patients with paroxysmal nocturnal haemoglobinuria and active haemolysis: an open-label, single-arm, phase 2, proof-of-concept trial

Published:2021-05 Issue:5 Volume:8 Page:e344-e354
ISSN:2352-3026
Container-title:The Lancet Haematology
language:en
Short-container-title:The Lancet Haematology

Author:

Risitano Antonio M,Röth Alexander,Soret Juliette,Frieri Camilla,de Fontbrune Flore Sicre,Marano Luana,Alashkar Ferras,Benajiba Lina,Marotta Serena,Rozenberg Izabela,Milojevic Julie,End Peter,Nidamarthy Prasanna K,Junge Guido,Peffault de Latour Régis

Funder

Novartis Institutes for BioMedical Research

Publisher

Elsevier BV

Subject

Hematology

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4. Advances in understanding the pathogenesis of acquired aplastic anaemia;Luzzatto;Br J Haematol,2018

5. Deficient biosynthesis of N-acetylglucosaminyl-phosphatidylinositol, the first intermediate of glycosyl phosphatidylinositol anchor biosynthesis, in cell lines established from patients with paroxysmal nocturnal haemoglobinuria;Takahashi;J Exp Med,1993

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