The histone deacetylase inhibitor, trichostatin A, reactivates the developmentally silenced γ globin expression in somatic cell hybrids and induces γ gene expression in adult BFUe cultures
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Hematology,Molecular Biology,Molecular Medicine
Reference15 articles.
1. Butyrate infusions in the ovine fetus delay the biologic clock for globin gene switching;Perrine;Proc. Natl. Acad. Sci. USA,1988
2. α-Amino-N-butyric acid stimulates fetal hemoglobin in the adult;Constantoulakis;Blood,1988
3. On the induction of fetal hemoglobin by butyrates: in vivo and in vitro studies with sodium butyrate and comparison of combination treatments with 5-AzaC and AraC;Constantoulakis;Blood,1989
4. Sodium butyrate enhances fetal globin gene expression in erythroid progenitors of patients with Hb SS and beta thalassemia;Perrine;Blood,1989
5. Sustained induction of fetal hemoglobin by pulse butyrate therapy in sickle cell disease;Atweh;Blood,1999
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3. β-Thalassemia Due to Intronic LINE-1 Insertion in theβ-GlobinGene (HBB): Molecular Mechanisms Underlying Reduced Transcript Levels of theβ-GlobinL1Allele;Human Mutation;2013-08-13
4. Chemical genetic strategy identifies histone deacetylase 1 (HDAC1) and HDAC2 as therapeutic targets in sickle cell disease;Proceedings of the National Academy of Sciences;2010-06-28
5. Non-Cancer Uses of Histone Deacetylase Inhibitors: Effects on Infectious Diseases and β-Hemoglobinopathies+;Current Topics in Medicinal Chemistry;2009-02-01
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