Mastocytaemia in cats: Prevalence, detection and quantification methods, haematological associations and potential implications in 30 cats with mast cell tumours

Abstract

The significance of mastocytaemia in cats is different from that in dogs because it appears exclusively associated with mast cell neoplasia. The prevalence of mastocytaemia was 0.05% of all feline submissions to a private laboratory and 43% in cats with mast cell neoplasia. None of 30 healthy cats had mastocytaemia. There was no sex bias or significant age difference between mastocytaemic and non-mastocytaemic cats with mast cell tumours (MCT). Buffy coat (BC) examination was the best screening method for detection of mastocytaemia but direct blood film examination was more accurate for quantifying degree of mastocytaemia. BC examination should be performed in all cases of suspected/known mast cell neoplasia as mastocytaemia was missed on nearly 30% of occasions when direct film examination only was used. Mastocytaemia was associated with decreased haematocrit (HCT) but not with other haematological parameters. Mastocytaemic cats can survive significant lengths of time (up to 27 months) even when splenectomy is not performed.