Central LIF gene therapy suppresses food intake, body weight, serum leptin and insulin for extended periods

Author:

Beretta Elena,Dhillon Harveen,Kalra Pushpa S,Kalra Satya P

Publisher

Elsevier BV

Subject

Cellular and Molecular Neuroscience,Endocrinology,Physiology,Biochemistry

Reference56 articles.

1. In vivo effect of recombinant human leukemia inhibitory factor in primates;Akiyama;Jpn. J. Cancer Res.,1997

2. Leukemia inhibitory factor-neuroimmune modulator of endocrine function;Auernhammer;Endocr. Rev.,2000

3. Leptin enters the brain by a saturable system independent of insulin;Banks;Peptides,1996

4. The full-length leptin receptor has signaling capabilities of interleukin-6-type cytokine receptors;Baumann;Proc. Natl. Acad. Sci. U.S.A.,1996

5. Beretta E, Dube MG, Dhillon H, Kalra PS, Kalra SP. Central leptin gene therapy in pre-pubertal rats reduces weight gain, metabolic hormones, blood leptin and insulin levels but augments energy expenditure post-pubertally for extended period. In: Proceedings of the SSIB Annual Meeting, Philadelphia, PA, 2001. p. 72 [Abstract].

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