Therapeutic implications of germline vulnerabilities in DNA repair for precision oncology

Author:

Shah Shreya M.,Demidova Elena V.,Lesh Randy W.,Hall Michael J.,Daly Mary B.,Meyer Joshua E.,Edelman Martin J.,Arora SanjeevaniORCID

Publisher

Elsevier BV

Subject

Radiology, Nuclear Medicine and imaging,Oncology,General Medicine

Reference227 articles.

1. Pathogenic Variants in Less Familiar Cancer Susceptibility Genes: What Happens After Genetic Testing?;Hall;JCO Precision Oncol,2018

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3. The underlying mechanism for the PARP and BRCA synthetic lethality: Clearing up the misunderstandings;Helleday;Mol Oncol,2011

4. FDA Approval Summary: Olaparib Monotherapy in Patients with Deleterious Germline BRCA-Mutated Advanced Ovarian Cancer Treated with Three or More Lines of Chemotherapy;Kim;Clin Cancer Res,2015

5. Trapping Poly(ADP-Ribose) Polymerase;Shen;J Pharmacol Exp Ther,2015

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