Depletion of intracellular glutathione by 1-methyl-2-nitrosoimidazole

Author:

Bérubé Luc R.,Farah Salim,McClelland Robert A.,Rauth Andrew M.

Publisher

Elsevier BV

Subject

Cancer Research,Radiology, Nuclear Medicine and imaging,Oncology,Radiation

Reference14 articles.

1. Keynote address: hypoxic cell sensitizers: clinical developments;Dische;Int. J. Radiat. Oncol. Biol. Phys.,1989

2. Oxidation of glutathione during hydroperoxide metabolism. A study using isolated hepatocytes and the glutathione reductase inhibitor 1,3-bis(2-chloroethyl)-1-nitrosourea;Eklow;Eur. J. Biochem.,1984

3. Aspects of the reduction of 1-methyl-2-nitroimidazole with glutathione and the reaction of 1-methyl-2-nitrosoimidazole with glutathione;Farah,1990

4. 4.Gipp, J. J.; McClelland, R. A.; Olive, P. L.; Mulcahy, R. T. DNA damage induced in cells by exposure to 1-methyl-2-nitrosoimidazole, a reductive metabolite of 1-methyl-2-nitroimidazole. Int. J. Radiat. Oncol. Biol. Phys. (In press).

5. Enhancement of melphalan (L-PAM) toxicity by reductive metabolites of 1-methyl-2-nitroimidazole, a model nitroimidazole chemosensitizing agent;Mulcahy;Biochem. Pharmacol.,1990

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