Gastrointestinal Safety of Coxibs and Outcomes Studies

Author:

Laine Loren

Publisher

Elsevier BV

Subject

Anesthesiology and Pain Medicine,Neurology (clinical),General Nursing

Reference13 articles.

1. In vivo effects of rofecoxib, a new cyclooxygenase (COX)-2 inhibitor, on gastric mucosal prostaglandin (PG) and serum thromboxane B2 (TXB2) synthesis in healthy humans;Cryer;Gastroenterology,1999

2. A randomized trial measuring fecal blood loss after treatment with rofecoxib, ibuprofen, or placebo in healthy subjects;Hunt;Am J Med,2000

3. COX-2 specific inhibition with MK-0966 25 or 50 mg Q.D. does not increase intestinal permeability;Bjarnason;Am J Gastroenterol,1998

4. A randomized trial comparing the effect of rofecoxib, a cyclooxygenase 2-specific inhibitor, with that of ibuprofen on the gastroduodenal mucosa of patients with osteoarthritis;Laine;Gastroenterology,1999

5. Comparison of the effect of rofecoxib (a cyclooxygenase 2 inhibitor), ibuprofen, and placebo on the gastroduodenal mucosa of patients with osteoarthritis;Hawkey;Arthritis Rheum,2000

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