Quality of life, patient satisfaction, and cardiovascular outcomes of the randomised 2 x 3 factorial Copenhagen insulin and Metformin therapy (CIMT) trial – A detailed statistical analysis plan

Author:

Olsen Markus HarboeORCID,Almdal Thomas P.,Madsbad Sten,Ovesen Christian,Gluud Christian,Sneppen Simone B.,Breum Leif,Hedetoft Christoffer,Krarup Thure,Lundby-Christensen Louise,Mathiesen Elisabeth R.,Røder Michael E.,Vestergaard Henrik,Wiinberg Niels,Jakobsen Janus C.

Funder

Novo Nordisk AS

Publisher

Elsevier BV

Subject

Pharmacology,General Medicine

Reference35 articles.

1. CIMT trial group, study rationale and design of the CIMT trial: the copenhagen insulin and metformin therapy trial;Lundby Christensen;Diabetes Obes. Metabol.,2009

2. Metformin versus placebo in combination with insulin analogues in patients with type 2 diabetes mellitus-the randomised, blinded Copenhagen Insulin and Metformin Therapy (CIMT) trial;Lundby-Christensen;BMJ Open,2016

3. Effects of biphasic, basal-bolus or basal insulin analogue treatments on carotid intima-media thickness in patients with type 2 diabetes mellitus: the randomised Copenhagen Insulin and Metformin Therapy (CIMT) trial;Lundby-Christensen;BMJ Open,2016

4. CIMT Trial Group 10, Genetic determinants of blood pressure traits are associated with carotid arterial thickening and plaque formation in patients with type 2 diabetes;Engelbrechtsen;Diabetes Vasc. Dis. Res.,2019

5. CIMT trial group, Prediction of carotid intima-media thickness and its relation to cardiovascular events in persons with type 2 diabetes;Winckler;J. Diabet. Complicat.,2020

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