PET Imaging of brain muscarinic receptors with 18F-Fluorobenzyl-Dexetimide: A first in human study

Author:

Rowe Christopher C.,Krishnadas Natasha,Ackermann Uwe,Doré Vincent,Goh Rachel Y.W.,Guzman Rodney,Chong Lee,Bozinovski Svetlana,Mulligan Rachel,Kanaan Richard,Dean Brian,Villemagne Victor L.

Publisher

Elsevier BV

Subject

Psychiatry and Mental health,Radiology Nuclear Medicine and imaging,Neuroscience (miscellaneous)

Reference26 articles.

1. 123I-iododexetimide preferentially binds to the muscarinic receptor subtype M1 in vivo;Bakker;J. Nucl. Med.,2015

2. Basal forebrain cholinergic circuits and signaling in cognition and cognitive decline;Ballinger;Neuron,2016

3. Human dosimetry and biodistribution of iodine-123-iododexetimide: a SPECT imaging agent for cholinergic muscarinic neuroreceptors;Boundy;J. Nucl. Med.,1995

4. Reduced posterior cingulate binding of I-123 iodo-dexetimide to muscarinic receptors in mild Alzheimer’s disease;Boundy;J. Clin. Neurosci.,2005

5. Decreased muscarinic receptors in the dorsolateral prefrontal cortex of subjects with schizophrenia;Dean;Mol. Psychiatry,2002

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