Roadmap to affinity-tuned antibodies for enhanced chimeric antigen receptor T cell function and selectivity-Reference-Cited by-同舟云学术

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Roadmap to affinity-tuned antibodies for enhanced chimeric antigen receptor T cell function and selectivity

Published:2022-07 Issue:7 Volume:40 Page:875-890
ISSN:0167-7799
Container-title:Trends in Biotechnology
language:en
Short-container-title:Trends in Biotechnology

Author:

Vander Mause Erica R.^ORCID,Atanackovic Djordje^ORCID,Lim Carol S.^ORCID,Luetkens Tim^ORCID

Funder

ALSAM Foundation

American Foundation for Pharmaceutical Education

Huntsman Cancer Institute

National Comprehensive Cancer Network

Publisher

Elsevier BV

Subject

Bioengineering,Biotechnology

Reference118 articles.

1. CD19 CAR T cells;Sadelain;Cell,2017

2. Anti-BCMA CAR T-cell therapy bb2121 in relapsed or refractory multiple myeloma;Raje;N. Engl. J. Med.,2019

3. FDA approves 100th monoclonal antibody product;Mullard;Nat. Rev. Drug Discov.,2021

4. Enhanced CAR T cell expansion and prolonged persistence in pediatric patients with ALL treated with a low-affinity CD19 CAR;Ghorashian;Nat. Med.,2019

5. Reduced functional avidity promotes central and effector memory CD4 T cell responses to tumor-associated antigens;Caserta;J. Immunol.,2010

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3. Therapeutic potential of third-generation chimeric antigen receptor T cells targeting B cell maturation antigen for treating multiple myeloma;Clinical and Experimental Medicine;2024-04-29

4. Differential Roles of Kinetic On- and Off-Rates in T-Cell Receptor Signal Integration Revealed with a Modified Fab’-DNA Ligand;2024-04-02

5. Novel CAR-T cells targeting TRKB for the treatment of solid cancer;Apoptosis;2024-03-18

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