Adenosine receptor Adora2b antagonism attenuates Brucella abortus 544 infection in professional phagocyte RAW 264.7 cells and BALB/c mice

Author:

Reyes Alisha Wehdnesday Bernardo,Vu Son Hai,Huy Tran Xuan Ngoc,Min WonGi,Lee Hu Jang,Chang Hong Hee,Lee John Hwa,Kim Suk

Funder

Basic Science Research Program through the National Research Foundation of Korea

Ministry of Education

Publisher

Elsevier BV

Subject

General Veterinary,General Medicine,Microbiology

Reference34 articles.

1. Immunopathology of Brucella infection;Baldi;Recent Pat. Antiinfect. Drug Discov.,2013

2. Brucella abortus inhibits IFN-γ-induced FcγRI expression and FcγRI-restricted phagocytosis via toll-like receptor 2 on human monocytes/macrophages;Barrionuevo;Microbes Infect.,2011

3. A2B adenosine receptor blockade enhances macrophage-mediated bacterial phagocytosis and improves polymicrobial sepsis survival in mice;Belikoff;J. Immunol.,2011

4. Host susceptibility to Brucella abortus infection is more pronounced in IFN-γ knockout than IL-12/β2-microglobulin double-deficient mice;Brandao;J. Immunol. Res.,2012

5. Brucella species release a specific, protease-sensitive, inhibitor of TNF-alpha expression, active on human macrophage-like cells;Canon;J. Immunol.,1996

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