PA-X protein of H5N1 avian influenza virus inhibits NF-kappaB activity, a potential mechanism for PA-X counteracting the host innate immune responses

Author:

Hu Jiao,Kong Ming,Cui Zhu,Gao Zhao,Ma Chunxi,Hu Zenglei,Jiao Xinan,Liu Xiufan

Funder

National Natural Science Foundation of China

National Key Research and Development Project of China

China Postdoctoral Science Foundation

Postdoctoral Science Foundation of Jiangsu Province, China

“Qing Lan Project” of Higher Education Institutions of Jiangsu Province, China

“High-end talent support program” of Yangzhou University, China

Earmarked Fund For China Agriculture Research System

Fund for Academic Science and Technology Innovation of College students

Priority Academic Program Development of Jiangsu Higher Education Institutions, China

Publisher

Elsevier BV

Subject

General Veterinary,General Medicine,Microbiology

Reference83 articles.

1. IkappaB-mediated inhibition of virus-induced beta interferon transcription;Algarte;J. Virol.,1999

2. NF-kappaB signaling and human disease;Aradhya;Curr. Opin. Genet. Dev.,2001

3. Inducible nuclear expression of newly synthesized I kappa B alpha negatively regulates DNA-binding and transcriptional activities of NF-kappa B;Arenzana-Seisdedos;Mol. Cell Biol.,1995

4. Nuclear localization of I kappa B alpha promotes active transport of NF-kappa B from the nucleus to the cytoplasm;Arenzana-Seisdedos;J. Cell Sci.,1997

5. The NF-kappa B and I kappa B proteins: new discoveries and insights;Baldwin;Annu. Rev. Immunol.,1996

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