Mucosally administered Lactobacillus surface-displayed influenza antigens (sM2 and HA2) with cholera toxin subunit A1 (CTA1) Induce broadly protective immune responses against divergent influenza subtypes

Author:

Li Rui,Chowdhury Mohammed Y.E.,Kim Jae-Hoon,Kim Tae-Hwan,Pathinayake Prabuddha,Koo Wan-Seo,Park Min-Eun,Yoon Ji-Eun,Roh Jong-Bok,Hong Seung-Pyo,Sung Moon-Hee,Lee Jong-Soo,Kim Chul-Joong

Publisher

Elsevier BV

Subject

General Veterinary,General Medicine,Microbiology

Reference74 articles.

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2. The ADP-ribosylating CTA1-DD adjuvant enhances T cell-dependent and independent responses by direct action on B cells involving anti-apoptotic Bcl-2- and germinal center-promoting effects;Agren;J. Immunol.,2000

3. Genetically engineered nontoxic vaccine adjuvant that combines B cell targeting with immunomodulation by cholera toxin A1 subunit;Agren;J. Immunol.,1997

4. Adjuvanticity of the cholera toxin A1-based gene fusion protein, CTA1-DD, is critically dependent on the ADP-ribosyltransferase and Ig-binding activity;Agren;J. Immunol.,1999

5. Universal Vaccine based on ectodomain of matrix protein 2 of influenza A: Fc receptors and alveolar macrophages mediate protection;EI Bakkouri;J. Immunol.,2011

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