Alkaline phosphatase and liver fibrosis at diagnosis are associated with deep response to ursodeoxycholic acid in primary biliary cholangitis

Author:

Cançado Guilherme Grossi Lopes,Fucuta Patrícia da Silva,Gomes Nathalia Mota de Faria,Couto Cláudia Alves,Cançado Eduardo Luiz Rachid,Terrabuio Debora Raquel Benedita,Villela‑Nogueira Cristiane Alves,Braga Michelle Harriz,Nardelli Mateus Jorge,Faria Luciana Costa,Oliveira Elze Maria Gomes,Rotman Vivian,Oliveira Maria Beatriz,Cunha Simone Muniz Carvalho Fernandes da,Silva Marlone Cunha da,Mendes Liliana Sampaio Costa,Ivantes Claudia Alexandra Pontes,Codes Liana,de Almeida e Borges Valéria Ferreira,Pace Fabio Heleno de Lima,Pessôa Mário Guimarães,Signorelli Izabelle Venturini,Coral Gabriela Perdomo,Bittencourt Paulo Lisboa,Ferraz Maria Lucia Gomes

Publisher

Elsevier BV

Reference16 articles.

1. Primary biliary cholangitis: pathogenesis and therapeutic opportunities;Gulamhusein;Nat Rev Gastroenterol Hepatol,2020

2. Ursodeoxycholic acid therapy and liver transplant-free survival in patients with primary biliary cholangitis;Harms;J Hepatol,2019

3. Goals of treatment for improved survival in primary biliary cholangitis: treatment target should be bilirubin within the normal range and normalization of alkaline phosphatase;Murillo Perez;Am J Gastroenterol,2020

4. Adequate versus deep response to ursodeoxycholic acid in primary biliary cholangitis: to what extent and under what conditions is normal alkaline phosphatase level associated with complication-free survival gain?;Corpechot;Hepatology,2024

5. New treatment paradigms in primary biliary cholangitis;Levy;Clin Gastroenterol Hepatol,2023

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