CPP, a new potent and selective NMDA antagonist. Depression of central neuron responses, affinity for [3H]d-AP5 binding sites on brain membranes and anticonvulsant activity

Author:

Davies J.,Evans R.H.,Herrling P.L.,Jones A.W.,Olverman H.J.,Pook P.,Watkins J.C.

Publisher

Elsevier BV

Subject

Developmental Biology,Clinical Neurology,Molecular Biology,General Neuroscience

Reference20 articles.

1. Chapman, A.G., Meldrum, B.S., Nanji, M.J. and Watkins, J.C., Anticonvulsant and neurochemical action in DBA/2 mice of a novel piperazine derivative that acts on the NMDA receptor,Soc. Neuroscie. Abstr., in press.

2. Davies, J., Miller, A.S. and Sheardown, M.J., Amino acid receptor mediated excitatory synpatic transmission in the cat red nucleus,J. Physiol. (London), in press.

3. Recent advances in the pharmacology of excitatory amino acids in the mammalian central nervous system;Davies,1983

4. 2-Amino-5-phosphonovalerate (2APV), a potent and selective antagonist of amino acid-induced and synaptic excitation;Davies;Neurosci. Lett.,1981

5. Actions ofd andl forms of 2-Amino-5-phosphonovalerate and 2-amino-4-phosphonobutyrate in the cat spinal cord;Davies;Brain Research,1982

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