A simple and rapid method for preliminary evaluation of in vivo efficacy of anti-HIV compounds in mice

Author:

Sato Akihiko,Kodama Makoto,Abe Kenji,Miki Shigeru,Nishimura Miyuki,Suyama Akemi,Ogata Masaru,Toyoda Tatsuo,Sugimoto Hirohiko,Yoshie Osamu,Fujiwara Tamio

Publisher

Elsevier BV

Subject

Virology,Pharmacology

Reference19 articles.

1. Anomalous accumulation and decay of 2′,3′-dideoxyadenosine-5′-triphosphate in human T-cell cultures exposed to the anti-HIV drug 2′,3′-dideoxyinosine;Ahluwalia;Drug Metab. Dispos. Biol. Fate Chem.,1993

2. Preformulation solubility and kinetic studies of 2′,3′-dideoxypurine nucleosides: potential anti-AIDS agents;Anderson;Int. J. Pharm.,1988

3. Potent and selective inhibition of human immunodeficiency virus type 1 (HIV-1) by 5-ethyl-6-phenylthiouracil derivatives through their interaction with the HIV-1 reverse transcriptase;Baba,1991

4. Long-term persistent infection of macaques monkeys with the simian immunodeficiency virus;Daniel;J. Gen. Virol.,1987

5. Pharmacokinetics of R82913 in AIDS patient: a phase I dose-finding study of oral administration compared with intravenous infusion;De Wit;Antimicrob. Agents Chemother.,1992

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