Phosphonylmethoxyalkyl purine and pyrimidine derivatives for treatment of opportunistic cytomegalovirus and herpes simplex virus infections in murine AIDS

Author:

De Castro Laura M.,Kern Earl R.,De Clercq Erik,Ghaffar Abdul,Mayer Eugene P.,Vogt Peggy E.,Gangemi J.David

Publisher

Elsevier BV

Subject

Virology,Pharmacology

Reference42 articles.

1. Cytomegalovirus infection in immunocompromised guinea pigs: a model for testing antiviral agents in vivo;Aquino-de Jesus;Antiviral Res.,1989

2. Marked in vivo antiretrovirus activity of 9-(2-phosphonylmethoxyethyl) adenine, a selective anti-human immunodeficiency virus agent;Balzarini,1989

3. Intracellular metabolism and mechanism of anti-retrovirus action of 9-(2-phosphonylmethoxyethyl)adenine (PMEA), a potent anti-HSV compound;Balzarini,1990

4. Synthesis and antiviral activity of phosphonylmethoxyethyl derivatives of purine and pyrimidine bases;Bronson,1989

5. Synthesis and antiviral activity of nucleotide analogues bearing the (S)-(3-hydroxy-2-phosphonylmethoxy) propyl moiety attached to adenine, guanine, and cytosine;Bronson,1989

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