Author:
Batty G.-D.,Li Q.,Huxley R.,Zoungas S.,Taylor B.-A.,Neal B.,de Galan B.,Woodward M.,Harrap S.-B.,Colagiuri S.,Patel A.,Chalmers J.
Abstract
AbstractObjectiveExamine the association of oral disease with future dementia/cognitive decline in a cohort of people with type 2 diabetes.MethodsA total of 11,140 men and women aged 55–88 years at study induction with type 2 diabetes participated in a baseline medical examination when they reported the number of natural teeth and days of bleeding gums. Dementia and cognitive decline were ascertained periodically during a 5-year follow-up.ResultsRelative to the group with the greatest number of teeth (more than or equal to 22), having no teeth was associated with the highest risk of both dementia (hazard ratio; 95% confidence interval: 1.48; 1.24, 1.78) and cognitive decline (1.39; 1.21, 1.59). Number of days of bleeding gums was unrelated to these outcomes.ConclusionsTooth loss was associated with an increased risk of both dementia and cognitive decline.
Publisher
Cambridge University Press (CUP)
Subject
Psychiatry and Mental health
Cited by
101 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献