A cross-continental analysis of weight gain, psychiatric diagnoses and medication use during inpatient psychiatric treatment. The international study on physical illness in mentally ill

Author:

Engelke Christina,Lange-Asschenfeldt Christian,Peter Stephanie,Kahl Kai G.,Frasch Karel,Larsen Jens I.,Bickel Graziella G.,Bork Bernhard,Jacobsen Bent A.,Wallenstein-Jensen Signe O.,Lauber Christoph,Mogensen Birthe,Nielsen Jørgen A.,Rössler Wulf,Tsuchiya Kenji J.,Toftegaard Kristian L.,Andersen Ulla A.,Uwakwe Richard,Munk-Jørgensen Povl,Cordes Joachim

Abstract

AbstractWeight gain among psychiatric inpatients is a widespread phenomenon. This change in body mass index (BMI) can be caused by several factors. Based on recent research, we assume the following factors are related to weight gain during psychiatric inpatient treatment: psychiatric medication, psychiatric diagnosis, sex, age, weight on admission and geographic region of treatment.876 of originally recruited 2328 patients met the criteria for our analysis. Patients were recruited and examined in mental health care centres in Nigeria (N=265), Japan (N=145) and Western-Europe (Denmark, Germany and Switzerland; N=466).There was a significant effect of psychiatric medication, psychiatric diagnoses and geographic region, but not age and sex, on BMI changes. Geographic region had a significant effect on BMI change, with Nigerian patients gaining significantly more weight than Japanese and Western European patients. Moreover, geographic region influenced the type of psychiatric medication prescribed and the psychiatric diagnoses. The diagnoses and psychiatric medication prescribed had a significant effect on BMI change.In conclusion, we consider weight gain as a multifactorial phenomenon that is influenced by several factors. One can discuss a number of explanations for our findings, such as different clinical practices in the geographical regions (prescribing or admission strategies and access-to-care aspects), as well as socio-economic and cultural differences.

Funder

Eli Lilly

Lundbeck

German Research Foundation and the German Bundesministerium für Bildung und Forschung

Foundation European Group for Research In Schizophrenia

ACADIA Pharmaceuticals Inc.

Boehringer Ingelheim Pharma GmbH & Co

KG, Otsuka Pharmaceutical Europe Ltd.

EnVivo Pharmaceuticals

Publisher

Cambridge University Press (CUP)

Subject

Psychiatry and Mental health

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