Author:
Hofer Alex,Baumgartner Susanne,Bodner Thomas,Edlinger Monika,Hummer Martina,Kemmler Georg,Rettenbacher Maria A.,Fleischhacker W. Wolfgang
Abstract
AbstractBackgroundCognitive dysfunction is increasingly considered to be the strongest clinical predictor of poor long-term outcome in schizophrenia. Associations have been found between the severity of cognitive deficits and social dysfunction, impairments in independent living, occupational limitations, and disturbances in quality of life (QOL).MethodsIn this cross-sectional study, the relationships of cognitive deficits and treatment outcomes in terms of QOL, needs, and psychosocial functioning were examined in 60 outpatients with schizophrenia who had a duration of illness over 2 years and had been treated with either clozapine or olanzapine for at least 6 months.ResultsThe present study suggests that cognitive functioning might be a predictor of work functioning/independent living outcome in stabilized patients with schizophrenia: deficits of visual memory and working memory were negatively associated with occupational functioning, and older patients lived independently and/or in a stable partnership more often. The patients' assessments of QOL and needs for care did not show any significant associations with cognitive functioning.DiscussionThese findings suggest that cognitive functioning is a key determinant of work functioning/independent living for stable outpatients with schizophrenia.
Publisher
Cambridge University Press (CUP)
Subject
Psychiatry and Mental health
Cited by
113 articles.
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