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Simultaneous optimization of inter- and intra-tablet coating variability in a lab-scale coating process via DEM-MC simulations

  • Published:2023-10 Issue: Volume:428 Page:118788
  • ISSN:0032-5910
  • Container-title:Powder Technology
  • language:en
  • Short-container-title:Powder Technology

Author:

Mostafaei Fatemeh,Khinast Johannes G.,Remmelgas Johan,Forgber Thomas

Funder

Österreichische Forschungsförderungsgesellschaft

Steirische Wirtschaftsförderungsgesellschaft

Bundesministerium für Klimaschutz, Umwelt, Energie, Mobilität, Innovation und Technologie

Bundesministerium für Digitalisierung und Wirtschaftsstandort

Publisher

Elsevier BV

Subject

General Chemical Engineering

Reference37 articles.

1. Immediate drug release dosage form: a review;Nyol;J. Drug Deliv. Ther.,2013

2. Delayed release tablet dissolution related to coating thickness by terahertz pulsed image mapping;Psimadas;J. Pharm. Sci.,2012

3. Identification of critical process variables for coating actives onto tablets via statistically designed experiments;Rege;Int. J. Pharm.,2002

4. Process optimization using design of experiments;Porter;Pharm. Technol.,1997

5. In situ, near real-time acquisition of particle motion in rotating pan coating equipment using imaging techniques;Sandadi;Chem. Eng. Sci.,2004

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